HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-methylisoxazole-4-carboxylate → 5-Methylisoxazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-methylisoxazole-4-carboxylate | HCID 7009317 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 5-Methylisoxazole-4-carboxylic acid | HCID 1425240 | 78.9% |
Reaction Steps
Ethyl 5-methylisoxazol-4-yl carboxylate (65 g) was heated under reflux in 10M HCl (500 ml) for 3 hours. On cooling the product crystallised out. This was filtered and dried giving 42 g of a white crystalline solid, m.p. 134°-136° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892963 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-a9c8b6f7578545e8abd28af815a73ad5 |
| Source note | uspto-grants-1990_01 |