HCID 28306209, compound → HCID 23686291, compound

HRID 329819Notes

Reaction equation

HRID 329819 reaction equation
[F:1][C:2]([F:9])([CH2:6][CH:7]=[CH2:8])[C:3]([O-:5])=[O:4].O(C)[Na:11]>CO>[F:1][C:2]([F:9])([CH2:6][CH:7]=[CH2:8])[C:3]([O-:5])=[O:4].[Na+:11]

Participants

4

Reactant 2

HCID 28306209HCID 28306209, compoundHCID 178418582HCID 178418582, compound

Product 1

HCID 23686291HCID 23686291, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

4,01 g (29.9 mmol) of 2,2-difluoro-4-pentenoate acid are dissolved in 20 ml of methanol, and 1 equivalent of NaOCH3 in methanol is added at room temperature (RT). After evaporation in the RE, 4.65 g (100%) of colourless crystals of melting point 168°-170° C. (decomposition) remain.

Workup

  1. customAfter evaporation in the RE, 4.65 g (100%) of colourless crystals of melting point 168°-170° C. (decomposition)

Sources & evidence

ORD record
ord-d3f794bb5082473c9d03269c5776d798
Source dataset
uspto-grants-1990_01
Patent number
US04892962

Reaction notes

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