HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diketene → HCID 19871257, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diketene | HCID 12661 | — |
| Reactant | 1H-1,4-Diazepine-1-ethanol, 4-(diphenylmethyl)hexahydro- | HCID 12236518 | — |
| Product | HCID 19871257 | HCID 19871257 | 81.8% |
Reaction Steps
4-Benzhydrylhomopiperazine-1-ethanol (2.6 g) was reacted with diketene in the same manner as Reference Example 1-(2) to give 2-(4-benzhydrylhomopiperazin-1-yl)ethyl acetoacetate as an oil (2.7 g, 81.8%). IR(Neat): 1735, 1715 cm-1. NMR(CDCl3)δ: 1.6-1.9(2H, m), 2.26(3H, s), 2.5-2.9(10H, m), 3.40(2H, s), 4.20(2H, t, J=6), 4.57(1H, s), 7.1-7.5(10H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892875 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-50a286d156e84ad7ba62c714baced431 |
| Source note | uspto-grants-1990_01 |