HRID329891

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12661

Diketene

C4H4O2

HCID15524146

未命名化合物

PRODUCTS

生成物

结构：CC(=O)CC(=O)OCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1

HCID19871233

3-[4-(Diphenylmethyl)piperazin-1-yl]propyl 3-oxobutanoate

C24H30N2O3

收率 96.3%

PROCEDURE

实验过程

4-Benzhydryl-1-piperazinepropanol was reacted with diketene in the same manner as Reference Example 2-(1) to give 3-(4-benzhydryl-1-piperazinyl)propyl acetoacetate as an oil. Yield 96.3%. NMR(CDCl3)δ: 1.62-1.98(2H, m), 3.40(2H, s), 4.16(2H, t, J=6.8), 4.20(1H, s), 7.10-7.49(10H, m).