HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diketene → 3-[4-(Diphenylmethyl)piperazin-1-yl]propyl 3-oxobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diketene | HCID 12661 | — |
| Reactant | 4-Benzhydryl-1-piperazinepropanol | HCID 15524146 | — |
| Product | 3-[4-(Diphenylmethyl)piperazin-1-yl]propyl 3-oxobutanoate | HCID 19871233 | 96.3% |
Reaction Steps
4-Benzhydryl-1-piperazinepropanol was reacted with diketene in the same manner as Reference Example 2-(1) to give 3-(4-benzhydryl-1-piperazinyl)propyl acetoacetate as an oil. Yield 96.3%. NMR(CDCl3)δ: 1.62-1.98(2H, m), 3.40(2H, s), 4.16(2H, t, J=6.8), 4.20(1H, s), 7.10-7.49(10H, m).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04892875 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-5d1d7222cced4e448625fd3b3718f5a1 |
| Source note | uspto-grants-1990_01 |