Sodium Hydroxide → Sodium 4-[3-(4-chlorophenyl)-1-(imidazol-1-ylmethyl)propylthio]benzoate

Participants

Reaction Steps

360 μl of a 1N aqueous solution of sodium hydroxide were added to a solution of 34 mg of methyl 4-[3-(4-chlorophenyl)-1-(imidazol-1-ylmethyl)propylthio]benzoate (prepared as described in Example 31) in 360 μl of methanol, and the resulting mixture was stirred at room temperature for 3 hours. The reaction mixture was then treated and purified by the same method as described in Example 8, to give 21 mg of the title compound as a colorless powder.

Provenance & Evidence