HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2,4,5-Trifluoro-3-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,4,5-Trifluoro-3-methylbenzoic acid | HCID 11805514 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2,4,5-Trifluoro-3-methylbenzoyl chloride | HCID 14052570 | — |
Reaction Steps
A mixture of 2,4,5-trifluoro-3-methylbenzoic acid (6.0 g), thionyl chloride (26 ml) and DMF (0.01 ml) was refluxed for 4 hours. Then excess thionyl chloride was removed under reduced pressure, the resulting residue was distilled under reduced pressure to give the title compound (4.51 g) as pale yellow liquid, bp 90°-92° C./40 mmHg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04894458 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-28cc12c301b1402093a08a2299c002c5 |
| Source note | uspto-grants-1990_01 |