反应详情

A mixture of 2,4,5-trifluoro-3-methylbenzoic acid (6.0 g), thionyl chloride (26 ml) and DMF (0.01 ml) was refluxed for 4 hours. Then excess thionyl chloride was removed under reduced pressure, the resulting residue was distilled under reduced pressure to give the title compound (4.51 g) as pale yellow liquid, bp 90°-92° C./40 mmHg.

1. temperaturewas refluxed for 4 hours
2. customThen excess thionyl chloride was removed under reduced pressure
3. distillationthe resulting residue was distilled under reduced pressure