Dichloromethane → HCID 85556120, compound

HRID 330227Notes

Reaction equation

HRID 330227 reaction equation
C([NH:8][CH2:9][CH:10]([CH2:12][S:13]([CH:16]([CH3:18])[CH3:17])(=[O:15])=[O:14])[OH:11])(OC(C)(C)C)=O.C(Cl)[Cl:20]>>[NH2:8][CH2:9][CH:10]([CH2:12][S:13]([CH:16]([CH3:18])[CH3:17])(=[O:15])=[O:14])[OH:11].[ClH:20]

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 131716254HCID 131716254, compound

Product 1

HCID 85556120HCID 85556120, compound

Procedure

BOC-NHCH2CH(OH)CH2SO2CH(CH3)2 (3.19 g, 11.35 mmole) was dissolved in 75 ml CH2Cl2 and purged with HCl gas over two hours. The mixture was stripped, triturated with ethyl ether, and filtered. The solid was washed with ethyl ether and dried giving 2.21 g of product.

Workup

  1. custompurged with HCl gas over two hours
  2. customtriturated with ethyl ether
  3. filtrationfiltered
  4. washThe solid was washed with ethyl ether
  5. customdried

Sources & evidence

ORD record
ord-20a2dd9e5e2640a29f7ddf190335c505
Source dataset
uspto-grants-1990_01
Patent number
US04895834

Reaction notes

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