Hydrochloric Acid → HCID 13013076, compound

Participants

Reaction Steps

According to the procedure of W. K. Anderson, et al., J. Chem. Soc., Perkin, 1, 1 (1976), a mixture of 2-(2-chloro-1-propen-3-yl)-4-fluorophenol (20.9 g, 0.112 mol) and concentrated hydrochloric acid (114 mL) was heated at 85°-89° C. for 24 hours. The mixture was cooled and diluted with ether. The ethereal layer was separated and washed with H2O, 5% KOH, and H2O, dried (MgSO4), and concentrated to give 12.40 g (74%) of product as a brown oil.

Provenance & Evidence