Ethanol → HCID 11287703, compound

HRID 330295Notes

Reaction equation

HRID 330295 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]2[N:7]3[CH:12]=[C:11]([CH2:13][OH:14])[N:10]=[C:8]3[S:9][C:5]=2[CH:4]=1.CCO>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]2[N:7]3[CH:12]=[C:11]([CH:13]=[O:14])[N:10]=[C:8]3[S:9][C:5]=2[CH:4]=1

Participants

5

Reactant 2

HCID 702EthanolHCID 11817172HCID 11817172, compound

Product 1

HCID 11287703HCID 11287703, compoundYield 79%

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6212ChloroformSolvent

Procedure

5.0 g (0.0225 mole) of the product of Step A and 10 g (0.115 mole) of manganese dioxide were stirred under reflux in 500 ml of chloroform for 2 hours. The mixture was filtered hot through celite and evaporated under reduced pressure to obtain 3.92 g (79% yield) of 7-methoxy-imidazo[2,1-b]benzothiazole-2-carboxaldehyde as colorless crystals melting at 214° to 215° C. (EtOH).

Workup

  1. filtrationThe mixture was filtered hot through celite
  2. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-6105d653a57a475c938ccfa0b4b62d87
Source dataset
uspto-grants-1990_01
Patent number
US04895863

Reaction notes

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