Acetic Acid → HCID 86743700, compound

HRID 330326Notes

Reaction equation

HRID 330326 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:10]2[CH:11]=[CH:12][C:13]3[O:17][C:16]([CH3:19])([CH3:18])[CH2:15][C:14]=3[CH:20]=2)=O)=[CH:4][CH:3]=1.O.[NH2:22][NH2:23].C(O)(=O)C>C(O)C>[CH3:18][C:16]1([CH3:19])[CH2:15][C:14]2[CH:20]=[C:10]([C:8](=[N:22][NH2:23])[C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)[CH:11]=[CH:12][C:13]=2[O:17]1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 24654Hydrazine hydrate (1:1)HCID 54257467HCID 54257467, compound

Product 1

HCID 86743700HCID 86743700, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This compound was prepared in a manner analogous to that of Example 1, Step D, using 1.4 grams (0.005 mole) of (4-chlorophenyl) (2,3-dihydro-2,2-dimethylbenzofuran-5-yl)ketone, 0.4 mL (0.008 mole) of hydrazine hydrate, and 0.3 mL of acetic acid in 50 mL of ethanol. The yield of (4-chlorophenyl) (2,3-dihydro-2,2-(dimethyl- benzofuran-5-yl) ketone hydrazone was 1.23 grams. The nmr spectrum was consistent with the proposed structure.

Workup

  1. customThis compound was prepared in a manner analogous to that of Example 1, Step D

Sources & evidence

ORD record
ord-052e1ac4ef0843228c4cd9734182452e
Source dataset
uspto-grants-1990_01
Patent number
US04895871

Reaction notes

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