HCID 67834280, compound → HCID 14458244, compound

HRID 330355Notes

Reaction equation

HRID 330355 reaction equation
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]([NH:9][N:10]=[CH:11]/[CH:12]=[CH:13]/[CH3:14])=[O:8]>C1(OC2C=CC=CC=2)C=CC=CC=1>[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]([N:9]1[CH:13]([CH3:14])[CH2:12][CH:11]=[N:10]1)=[O:8]

Participants

3

Reactant 1

HCID 67834280HCID 67834280, compound

Product 1

HCID 14458244HCID 14458244, compoundYield 36.8%

Reagents, catalysts & solvents 1

HCID 7583Diphenyl EtherSolvent

Procedure

A quantity of 3.8 g of this hydrazone was suspended in 10 ml of diphenyl ether, followed by stirring at 200°-220° C. (bath temperature) for 3 hours. After cooling, the reaction liquid was purified by silica gel column chromatography (ethyl acetate). Thus there was obtained 1.4 g of 1-pyrazinylcarbonyl-5-methyl-2-pyrazoline (mp. 77°-79° C.). The yield was 36.8%.

Workup

  1. temperatureAfter cooling
  2. customthe reaction liquid
  3. customwas purified by silica gel column chromatography (ethyl acetate)

Sources & evidence

ORD record
ord-3c10ef7aa0b74d558de276765711e792
Source dataset
uspto-grants-1990_01
Patent number
US04895947

Reaction notes

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