HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citric Acid → N-(2-Phenoxyethyl)-N-(2-phenylethyl)-N',N'-bis[2-(1-pyrrolidinyl)ethyl]urea citrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Proton sponge | HCID 88675 | — |
| Reactant | HCID 14855250 | HCID 14855250 | — |
| Reactant | HCID 19869583 | HCID 19869583 | — |
| Product | N-(2-Phenoxyethyl)-N-(2-phenylethyl)-N',N'-bis[2-(1-pyrrolidinyl)ethyl]urea citrate | HCID 17768614 | — |
Reaction Steps
N-(3-phenoxypropyl)benzeneethanamine (oil obtained in Preparation 29), phosgene (excess), Proton Sponge®, 2-(1-pyrrolidinyl)-N-[2-(1-pyrrolidinyl)ethyl]ethanamine, sodium carbonate, and treating with citric acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04895840 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-489bb97b5b674a8ab120227a6d5e2736 |
| Source note | uspto-grants-1990_01 |