反应详情

7-(4-Hydroxyphenyl)heptanoic acid (20 g) is subjected to similar catalytic reduction as Reference Example 5 in 80% ethanol. Ether is added to the crude product to give crystals. Recrystallization from ethanol-water and then from i-propanol-ether give trans-7-(4-hydroxycyclohexyl)heptanoic acid (7 g) as colorless needles, m.p. 123°-128° C.

1. customto give crystals
2. customRecrystallization from ethanol-water