HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 178525427, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 7-(4-Hydroxyphenyl)heptanoic acid | HCID 14822017 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178525427 | HCID 178525427 | 34.1% |
Reaction Steps
7-(4-Hydroxyphenyl)heptanoic acid (20 g) is subjected to similar catalytic reduction as Reference Example 5 in 80% ethanol. Ether is added to the crude product to give crystals. Recrystallization from ethanol-water and then from i-propanol-ether give trans-7-(4-hydroxycyclohexyl)heptanoic acid (7 g) as colorless needles, m.p. 123°-128° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04897420 |
| Source dataset | uspto-grants-1990_01 |
| ORD ID | ord-e064c7174bbe4c58a531eb28c1542710 |
| Source note | uspto-grants-1990_01 |