Sodium Bicarbonate → HCID 178441000, compound

Participants

Reaction Steps

In a 2% aqueous solution of sodium hydrogen carbonate (20 ml) was dissolved Compound 1 (1.0 g) and the solution was applied to a column of MCI gel HP-20P (product of Mitsubishi Chemical Ind., Japan, high porous polymer). The column was washed with distilled water until the effluent became neutral and, then, elution was carried out with acetone-water (20:80). The eluate (500 ml) was concentrated to about 1/3 of its initial volume and lyophilized to give 0.8 g (yield 76.2%) of the title compound as a colorless powder.

Provenance & Evidence