反应详情

0.20 g (1.04 mmol) 4-bromo-5-fluoro-pyridin-2-ol, 0.83 mL (10.4 mmol) ethyliodide and 0.43 g (1.56 mmol) Ag2CO3 are added to 5 mL DCM and stirred at r.t. over night. The reaction is quenched by the addition of water. DCM is added, the resulting mixture is filtered and the organic layer is separted, dried over MgSO4, filtered again and the solvent is removed in vacuo.

1. customThe reaction is quenched by the addition of water
2. additionDCM is added
3. filtrationthe resulting mixture is filtered
4. dry with materialdried over MgSO4
5. filtrationfiltered again
6. customthe solvent is removed in vacuo