Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 330786Generated: October 26, 2026

N,N-Dimethylaminoethyl chloride hydrochloride → N-[4-chloro-3-(2-dimethylamino-ethoxy)-phenyl]-acetamide

https://huagongshe.com/reaction/330786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-Dimethylaminoethyl chloride hydrochlorideHCID 11636816—
ReactantN-(4-Chloro-3-hydroxyphenyl)acetamideHCID 14122483—
ProductN-[4-chloro-3-(2-dimethylamino-ethoxy)-phenyl]-acetamideHCID 8668478180%

Reaction Steps

The compound 24a was prepared starting from 17a and 2-dimethylamino ethyl chloride hydrochloride, following the general procedure H, as given in Example 9, in 80% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877752B2
Source datasetuspto-grants-2014_11
ORD IDord-d9c152a8d2914cc79373a2b96b41a6d5
Source noteuspto-grants-2014_11