Hydrochloric Acid → 3,4-Dimethyl-2(3H)-thiazolone hydrazone hydrochloride

HRID 33083Notes

Reaction equation

HRID 33083 reaction equation
CC(=[N:4][N:5]=[C:6]1[N:10]([CH3:11])[C:9]([CH3:12])=[CH:8][S:7]1)C.[ClH:13]>>[ClH:13].[CH3:11][N:10]1[C:9]([CH3:12])=[CH:8][S:7][C:6]1=[N:5][NH2:4]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 734148093,4-Dimethyl-2(3H)thiazolone-(1-methylethylidene)hydrazone

Product 1

HCID 691153313,4-Dimethyl-2(3H)-thiazolone hydrazone hydrochloride

Procedure

3.5 g (19 mmol) of 3,4-dimethyl-2(3H)thiazolone-(1-methylethylidene) hydrazone from step A in 60 mL of 6 M hydrochloric acid was heated at 50° C. for 30 minutes. The reaction mixture was then concentrated, and the crude product was recrystallized from ethanol. This gave 2 g (60% of the theoretical) of a pink-colored powder.

Workup

  1. concentrationThe reaction mixture was then concentrated
  2. customthe crude product was recrystallized from ethanol

Sources & evidence

ORD record
ord-b87ae90efd0f4abfb7b1febbd5245f67
Source dataset
uspto-grants-2008_09
Patent number
US07429274B2

Reaction notes

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