反应详情

To 110 mg (0.5 mmol) of methyl 2,5-dichloro-3-aminobenzoate were added 190 mg (0.5 mmol) of HATU, 70 mg (0.5 mmol) of HOAt, 152 mg (0.5 mmol) of Boc-Glu-OtBu hydrochloride, 0.21 ml (1.5 mmol) of triethylamine and 2 ml of dichloromethane. The mixture was stirred at room temperature overnight.