反应详情

7.3 g of 1,4-difluoro-2-nitrobenzene are slowly added to 30 ml of a 40% aqueous methylamine solution whilst cooling with ice and the reaction mixture is stirred for 1 hour at ambient temperature. The precipitated product is suction filtered and recrystallised from water and ethanol. 6.3 g product are obtained as a solid. M.p=74-76° C.

1. temperaturewhilst cooling with ice
2. filtrationfiltered
3. customrecrystallised from water and ethanol