反应详情

The indanone compound of formula 6 prepared in Step 3, NBS (2 to 3 eq), and AIBN (1 to 0.2 eq) are dissolved in CCl4. Then, the mixture is allowed to reflux for 30 min to 1 h with stirring and then is further irradiated by a tungsten lamp (375 W) for 1 to 2 h with stirring, to obtain the 2-bromo-1H-indenone of formula 7. In other way, the mixture may be allowed to reflux for 2 to 9 h with stirring while being irradiated by a tungsten lamp (375 W), to obtain the 2-bromo-1H-indenone of formula 7.

1. temperatureto reflux for 30 min to 1 h
2. customis further irradiated by a tungsten lamp (375 W) for 1 to 2 h
3. stirringwith stirring