HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 1-(2-Bromo-4-methoxyphenyl)ethan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 3-Bromoanisole | HCID 16971 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Carbon Disulfide | HCID 6348 | — |
| Product | 1-(2-Bromo-4-methoxyphenyl)ethan-1-one | HCID 10657006 | — |
Reaction Steps
Acetyl chloride (1 to 1.2 eq) and AlCl3 (1 to 1.2 eq) are mixed with carbon disulfide, 3-bromoanisole dissolved in carbon disulfide is added thereto. The resulting mixture is stirred for 10 to 16 h at room temperature, to obtain 1-(2-bromo-4-methoxyphenyl)ethanone of formula 14.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-9bf2e95985fb4b7081ca472bdd9182b0 |
| Source note | uspto-grants-2014_11 |