反应详情

The indenone compound of formula 16 prepared in Step 3 is dissolved in CCl4, N-bromosuccinimide (1 to 1.2 eq) and 2,2′-azobisisobutyronitrile (10 to 15 wt %) are added thereto. The resulting mixture is allowed to reflux for 2 to 3 h with stirring, to obtain the 2-bromoindenone of formula 17.

1. temperatureto reflux for 2 to 3 h