HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-(2-Morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one hydrochloride salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 6-(2-morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one | HCID 50940509 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 6-(2-Morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one hydrochloride salt | HCID 70312620 | — |
Reaction Steps
6-(2-Morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one (500 mg, 1.21 mmol) obtained in Step 7 was placed into a flask and dissolved in CH2Cl2 (4.0 mL). To the resulting solution was added 1.0M HCl in diethyl ether (1.21 mL, 1 eq). The solvents were removed by rotary evaporation under reduced pressure to give the desired product in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-36348c8524db40d7ba1d0b22bfb36247 |
| Source note | uspto-grants-2014_11 |