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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331280Generated: October 30, 2026

3-(4-(Trifluoromethyl)phenyl)-2,3-dihydro-6-hydroxyinden-1-one → 1-(4-(Trifluoromethyl)phenyl)-2,3-dihydro-3-oxo-1H-inden-5-yl acetate

https://huagongshe.com/reaction/331280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-(Trifluoromethyl)phenyl)-2,3-dihydro-6-hydroxyinden-1-oneHCID 70307407—
Reactant2,3-Dihydro-6-hydroxy-3-phenylinden-1-oneHCID 70307501—
Product1-(4-(Trifluoromethyl)phenyl)-2,3-dihydro-3-oxo-1H-inden-5-yl acetateHCID 7031279599%

Reaction Steps

The procedure of Step 3 of Example 1 was repeated except for using 3-(4-(trifluoromethyl)phenyl)-2,3-dihydro-6-hydroxyinden-1-one obtained in Step 2 as a starting material instead of 2,3-dihydro-6-hydroxy-3-phenylinden-1-one and being stirred for 3 h to obtain the title compound (99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877747B2
Source datasetuspto-grants-2014_11
ORD IDord-9cb761cc100140a9930418fe96fdcaae
Source noteuspto-grants-2014_11