HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-oxo-3-phenyl-1H-inden-6-yl acetate → 2-Bromo-3-(3,5-difluorophenyl)-6-hydroxy-1H-inden-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-oxo-3-phenyl-1H-inden-6-yl acetate | HCID 70313241 | — |
| Reactant | 2-Bromo-3-(3,5-difluorophenyl)-1-oxo-1H-inden-6-yl acetate | HCID 70314444 | — |
| Product | 2-Bromo-3-(3,5-difluorophenyl)-6-hydroxy-1H-inden-1-one | HCID 70316043 | 64% |
Reaction Steps
The procedure of Step 5 of Example 1 was repeated except for using 2-bromo-3-(3,5-difluorophenyl)-1-oxo-1H-inden-6-yl acetate obtained in Step 4 as a starting material instead of 2-bromo-1-oxo-3-phenyl-1H-inden-6-yl acetate and being stirred for 2.5 h to obtain the title compound (64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-c12a60aa7b844d70ac8478e2964908b9 |
| Source note | uspto-grants-2014_11 |