HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(2-morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one → 3-(4-Chlorophenyl)-2-(3,4-difluorophenyl)-6-(2-(4-(methylsulfonyl)piperazin-1-yl)ethoxy)-1H-inden-1-one hydrochloride salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(2-morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one | HCID 50940509 | — |
| Reactant | 3-(4-Chlorophenyl)-2-(3,4-difluorophenyl)-6-(2-(4-(methylsulfonyl)piperazin-1-yl)ethoxy)-1H-inden-1-one | HCID 51001832 | — |
| Product | 3-(4-Chlorophenyl)-2-(3,4-difluorophenyl)-6-(2-(4-(methylsulfonyl)piperazin-1-yl)ethoxy)-1H-inden-1-one hydrochloride salt | HCID 70310581 | — |
Reaction Steps
The procedure of Step 8 of Example 1 was repeated except for using 3-(4-chlorophenyl)-2-(3,4-difluorophenyl)-6-(2-(4-(methylsulfonyl)piperazin-1-yl)ethoxy)-1H-inden-1-one obtained in Step 2 as a starting material instead of 6-(2-morpholinoethoxy)-3-phenyl-2-(pyridin-3-yl)-1H-inden-1-one to give the title compound in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877747B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-81c652fba7ef407fa6c7557892aada9f |
| Source note | uspto-grants-2014_11 |