HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1,4-Dioxan-2-yl)acetic acid → HCID 178520371, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1,4-Dioxan-2-yl)acetic acid | HCID 18469226 | — |
| Reactant | HCID 178478712 | HCID 178478712 | — |
| Product | HCID 178520371 | HCID 178520371 | — |
Reaction Steps
The title compound, off-white solid (81 mg, 62%), MS (ISP) m/z=455.4 [(M+H)+], mp 165° C., was prepared in accordance with the general method of example 1 from trans-4-[2-(4-benzofuran-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl-amine dihydrochloride (intermediate A) (115 mg, 0.29 mmol) and rac-(1,4-dioxan-2-yl)-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877778B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-788b3a8ce40f4f18b607a15cd8f6a5d3 |
| Source note | uspto-grants-2014_11 |