1-Hydroxycyclobutanecarboxylic acid → HCID 178523606, compound

Participants

Reaction Steps

The title compound, colorless semi-solid (73 mg, 69%), MS (ISP) m/z=427.4 [(M+H)+], was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 1-hydroxy-cyclobutane-carboxylic acid.

Provenance & Evidence