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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331456Generated: October 27, 2026

4-(Piperidin-1-yl)benzoic acid → HCID 178523595, compound

https://huagongshe.com/reaction/331456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Piperidin-1-yl)benzoic acidHCID 764599—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523595HCID 178523595—

Reaction Steps

The title compound, white solid (116 mg, 90%), MS (ISP) m/z=516.3 [(M+H)+], mp 248° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 4-piperidin-1-yl-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-ace013ccb0714eafb00f8df863afaab2
Source noteuspto-grants-2014_11