HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Chloro-5-(ethylsulfonyl)benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 178477630 | HCID 178477630 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 2-Chloro-5-(ethylsulfonyl)benzoxazole | HCID 58906316 | — |
Reaction Steps
8 mmol of 5-Ethanesulfonyl-benzooxazole-2-thiol were dissolved in 10 ml of thionyl chloride. 1 drop of N,N-dimethylformamide is added and the reaction mixture hold at 65° for 45 min. Evaporation of the solvent yields the title compound as brownish solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429585B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-c56e0eb749eb40fe866efc426817aff3 |
| Source note | uspto-grants-2008_09 |