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HRID331461

反应详情

EQUATION

反应方程式

HRID 331461 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C1CC1(F)F
HCID2782823

2,2-Difluorocyclopropanecarboxylic acid

C4H4F2O2

结构：Cl.Cl.N[C@H]1CC[C@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1
HCID178478710

未命名化合物

2 次

PRODUCTS

生成物

1
结构：O=C(N[C@H]1CC[C@H](CCN2CCC(c3cccc4c3CCO4)CC2)CC1)C1CC1(F)F
HCID178523583

未命名化合物

PROCEDURE

实验过程

The title compound, light yellow solid (79 mg, 73%), MS (ISP) m/z=433.4 [(M+H)+], mp 199° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2,2-difluoro-cyclopropane-carboxylic acid.