HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Isobutoxy-5-methanesulfonyl-benzoic acid → [4-(5-Ethanesulfonyl-benzoxazol-2-yl)-piperazin-1-yl]-(2-isobutoxy-5-methanesulfonyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Isobutoxy-5-methanesulfonyl-benzoic acid | HCID 23503110 | — |
| Reactant | 5-Ethanesulfonyl-2-piperazin-1-yl-benzoxazole hydrochloride | HCID 68896068 | — |
| Product | [4-(5-Ethanesulfonyl-benzoxazol-2-yl)-piperazin-1-yl]-(2-isobutoxy-5-methanesulfonyl-phenyl)-methanone | HCID 58906319 | — |
Reaction Steps
Prepared in analogy to example 1.1 b) from 2-isobutoxy-5-methanesulfonyl-benzoic acid (Example 2.4) and 5-ethanesulfonyl-2-piperazin-1-yl-benzoxazole hydrochloride. The crude material was purified by chromatography (SiO2, ethyl acetate) to yield the title compound as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429585B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-9098cd3818074b9d9d2ecb7c37892ce5 |
| Source note | uspto-grants-2008_09 |