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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331492Generated: October 27, 2026

4-Pyridin-3-yl-benzoic acid → HCID 178523588, compound

https://huagongshe.com/reaction/331492

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Pyridin-3-yl-benzoic acidHCID 1515244—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178523588HCID 178523588—

Reaction Steps

The title compound, off-white solid (54 mg, 53%), MS (ISP) m/z=510.5 [(M+H)+], mp 224° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 4-pyridin-3-yl-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-6cfdc9a36ddd4b2991cb3eef5c08203a
Source noteuspto-grants-2014_11