反应详情

The title compound, white solid (107 mg, 88%), MS (ISP) m/z=488.4 [(M+H)+], mp 214° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2-benzo[d]isoxazol-3-yl-acetic acid.