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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 331493Generated: October 26, 2026

2-(1,2-Benzoxazol-3-yl)acetic acid → HCID 178520399, compound

https://huagongshe.com/reaction/331493

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1,2-Benzoxazol-3-yl)acetic acidHCID 301729—
ReactantHCID 178478710HCID 178478710—
ProductHCID 178520399HCID 178520399—

Reaction Steps

The title compound, white solid (107 mg, 88%), MS (ISP) m/z=488.4 [(M+H)+], mp 214° C., was prepared in accordance with the general method of example 1 from trans-4-{2-[4-(2,3-dihydro-benzofuran-4-yl)-piperidin-1-yl]-ethyl}-cyclohexylamine dihydrochloride (intermediate B) (100 mg, 0.25 mmol) and 2-benzo[d]isoxazol-3-yl-acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08877778B2
Source datasetuspto-grants-2014_11
ORD IDord-4a934100222044679fc1aefca919ddd8
Source noteuspto-grants-2014_11