HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Isopropoxy-5-methylsulfonylbenzoic acid → HCID 58906307, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Isopropoxy-5-methylsulfonylbenzoic acid | HCID 21100237 | — |
| Reactant | 2-Piperazin-1-yl-benzothiazole-4-carboxylic acid methyl ester hydrochloride | HCID 68972287 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58906307 | HCID 58906307 | — |
Reaction Steps
Prepared in analogy to example 1.1 b) from 2-isopropoxy-5-methanesulfonyl-benzoic acid (Example 2.2) and 2-Piperazin-1-yl-benzothiazole-4-carboxylic acid methyl ester hydrochloride in tetrahydrofuran. The crude material was purified by chromatography (SiO2, heptane/ethyl acetate), and the residue was then triturated in ether to yield the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429585B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-4ab9aa2551a14e6084c107e56cd16f4e |
| Source note | uspto-grants-2008_09 |