HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Aminocyclopropanecarbonitrile → HCID 57520474, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Aminocyclopropanecarbonitrile | HCID 556888 | — |
| Reactant | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| Product | HCID 57520474 | HCID 57520474 | 51% |
Reaction Steps
As described for example 191, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using 1-amino-1-cyclopropanecarbonitrile instead of 2-aminoethyl isopropylether, to the title compound (61 mg, 51%) which was obtained as a white solid. MS: m/e=375.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877782B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-e9560cb13e3b4ff08c023a65f903a948 |
| Source note | uspto-grants-2014_11 |