참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 7-Methoxy-2,3,4,5-tetrahydro-1h-3-benzazepine | HCID 13853348 | — |
| 생성물 | 2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol hydrobromide | HCID 23331391 | — |
반응 단계
7-Methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine (10 g) (known from M. Kanao et al., Chem. Pharm. Bull. 1982, 30, 180-188) in 48% aqueous hydrobromic acid (350 ml) was allowed to stir at 100° C. for 4 h. The mixture was cooled to 20° C. then evaporated to dryness in vacuo to give the title compound (14.5 g) as a brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07429579B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_09 |
|---|
| ORD ID | ord-27c501d0fc8f43148348c03bf20cd060 |
|---|
| 출처 메모 | uspto-grants-2008_09 |
|---|
