HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzofuran-2-sulfonyl chloride → N-(5-chloro-2-{[2-(1H-pyrazol-4-yl)ethyl]thio}phenyl)-1-benzofuran-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzofuran-2-sulfonyl chloride | HCID 2795172 | — |
| Reactant | 2-((2-(1H-pyrazol-4-yl)ethyl)thio)-5-chloroaniline | HCID 67972877 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(5-chloro-2-{[2-(1H-pyrazol-4-yl)ethyl]thio}phenyl)-1-benzofuran-2-sulfonamide | HCID 67972412 | 45.9% |
Reaction Steps
Following General Procedure B, the title compound (123 mg) was prepared from 2-((2-(1H-pyrazol-4-yl)ethyl)thio)-5-chloroaniline (157 mg, 0.618 mmol) and benzofuran-2-sulfonyl chloride (133 mg, 0.618 mmol) in pyridine (3 ml).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877804B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-11741cdc7a724b6a9187fa537fa4fa2e |
| Source note | uspto-grants-2014_11 |