Pyridine → 3851-91-0

HRID 332593Notes

Reaction equation

HRID 332593 reaction equation
Cl[CH2:2][CH2:3][S:4](Cl)(=[O:6])=[O:5].[CH:8]([OH:11])([CH3:10])[CH3:9].N1C=CC=CC=1>ClCCl>[CH:8]([O:11][S:4]([CH:3]=[CH2:2])(=[O:6])=[O:5])([CH3:10])[CH3:9]

Participants

5

Reactant 3

HCID 1049PyridineHCID 3776IsopropanolHCID 15385Ethanesulfonylchloride, 2-chloro-

Product 1

HCID 122599943851-91-0

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2-Chloroethylsulfonyl chloride (2 g, 12.3 mmol), isopropanol (1 mL), and pyridine (2.7 mL) were dissolved in dichloromethane (20 mL), and the mixture was stirred at room temperature for 3 hours. The reaction mixture was washed successively with 1N hydrochloric acid and water, and the organic layer was dried over anhydrous magnesium sulfate. The drying agent was filtered, and the solvent was evaporated to give the title compound (1.06 g).

Workup

  1. washThe reaction mixture was washed successively with 1N hydrochloric acid and water
  2. dry with materialthe organic layer was dried over anhydrous magnesium sulfate
  3. filtrationThe drying agent was filtered
  4. customthe solvent was evaporated

Sources & evidence

ORD record
ord-f9cb4e839e2140daaf268dc37954fd6e
Source dataset
uspto-grants-2014_11
Patent number
US08877805B2

Reaction notes

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