HCID 77934570, compound → HCID 70869380, compound

HRID 332624Notes

Reaction equation

[C:1]([O:5][C:6]([C:8]([CH3:24])=[CH:9][C:10]1[S:14][C:13]([CH2:15][O:16][Si:17]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:19])[CH3:18])=[N:12][CH:11]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>C(O)C.[Pd]>[C:1]([O:5][C:6]([CH:8]([CH3:24])[CH2:9][C:10]1[S:14][C:13]([CH2:15][O:16][Si:17]([C:20]([CH3:23])([CH3:22])[CH3:21])([CH3:18])[CH3:19])=[N:12][CH:11]=1)=[O:7])([CH3:2])([CH3:4])[CH3:3]

Participants

Conditions

Temperature: 50 °C

Procedure

The compound (0.5 g, 1.4 mmol) obtained in step 3 was dissolved in ethanol (20 mL), palladium/carbon (0.1 g) was added, and the mixture was stirred at 50° C. for 20 hours under a hydrogen atmosphere (55 psi). The reaction mixture was filtered, and the solvent was evaporated under reduced pressure to give the title compound (0.3 g).

Workup

filtrationThe reaction mixture was filtered
customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record: ord-6015b547594349d9b02d899d458af548
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08877805B2

Reaction notes

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