HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 33265Generated: October 25, 2026
Tert-butyl 2-diazoacetate → HCID 178496244, compound
https://huagongshe.com/reaction/33265
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tert-butyl 2-diazoacetate | HCID 5097903 | — |
| Reactant | 3-[2-(2-Methoxyethoxy)ethoxy]prop-1-yne | HCID 18381683 | — |
| Product | HCID 178496244 | HCID 178496244 | — |
Reaction Steps
To a solution containing approx. 2.5 g 3-[2-(2-Methoxy-ethoxy)-ethoxy]-propyne, 2.8 g Diazo-acetic acid tert-butyl ester were added and the mixture was heated to 70° C. for 5 days. Then the solution was concentrated under reduced pressure and directly purified by chromatography on silica eluting with a n-heptane/ethyl acetate gradient. Yield: 1.7 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07429581B2 |
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| Source dataset | uspto-grants-2008_09 |
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| ORD ID | ord-5dcdf0e1a84744839a7df22d5b6dc47e |
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| Source note | uspto-grants-2008_09 |
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