Hydrochloric Acid → HCID 71257117, compound

Participants

Reaction Steps

To a solution of tert-butyl((3-((4′-((1,3-dioxolan-2-yl)methyl)-[1,1′-biphenyl]-3-yl)methoxy)phenyl)(phenyl)methyl)carbamate (1.44 g, 2.6 mmol) in methanol (6.5 mL), was added hydrogen chloride in dioxan (6.5 mL). The reaction mixture was stirred at ambient temperature for 16 hours. The solvent was evaporated to afford a mixture of the title compound and the corresponding dimethyl acetal. The material was used in the next step without further purification.

Provenance & Evidence