HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine → 1-(4-fluorophenyl)-N-methylcyclohexanecarboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | 1-(4-Fluorophenyl)cyclohexane-1-carboxylic acid | HCID 736136 | — |
| Produkt | 1-(4-fluorophenyl)-N-methylcyclohexanecarboxamide | HCID 47398508 | 86% |
Reaktionsschritte
The title compound was synthesized from 1-(4-fluorophenyl)cyclohexane-carboxylic acid (222 mg, 1 mmol) and methylamine (1 mL, 1M in THF, 1 eq) according to General Procedure G. The crude product was purified by silica gel column chromatography to give the amide (202.6 mg, 86%) as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08877975B2 |
| Quelldatensatz | uspto-grants-2014_11 |
| ORD ID | ord-34f5ab35e34a48338704b61c733c477f |
| Quellennotiz | uspto-grants-2014_11 |