HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178424507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | [(S)-2-(3'-methyl-biphenyl-4-yl)-1-(1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester | HCID 178424510 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178424507 | HCID 178424507 | — |
Reaction Steps
[(S)-2-(3′-Methyl-biphenyl-4-yl)-1-(1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester (560 mg, 1.48 mmol) was treated with 4M HCl in dioxane (10 mL) at room temperature for 2 hours. The reaction mixture was concentrated in vacuo to give (S)-2-(3′-methyl-biphenyl-4-yl)-1-(1H-tetrazol-5-yl)-ethylamine hydrochloride; MS: m/z (MH+) 280; Retention time=1.14 min. (condition A).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08877815B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-db5ad15514b5499ca45e7bd5e7283735 |
| Source note | uspto-grants-2014_11 |