Hydrochloric Acid → HCID 66987930, compound

Participants

Reaction Steps

549 mg (1.7 mmol) of tert-butyl 4-cyclohexyl-4-propionylpiperidine-1-carboxylate are dissolved in 2 mL (17 mmol) of 4N hydrogen chloride in ethyl acetate. The reaction mixture is stirred for 6 hours at room temperature. The solvents are evaporated off. The residue is taken up in ether and filtered off. 395 mg of 4-cyclohexyl-4-propionylpiperidine hydrochloride in the form of a white powder are obtained in a yield of 90%.

Provenance & Evidence