Benzaldehyde → 2-(Benzylideneamino)phenol

HRID 333528Notes

Reaction equation

HRID 333528 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].[CH:9](=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C(O)C>[CH:9](=[N:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 58012-Aminophenol

Product 1

HCID 2198092-(Benzylideneamino)phenol

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 2-aminophenol (28.55 g, 261.61 mmol) in ethanol (40 mL), was added benzaldehyde (30 mL, 31.32 g, 295.14 mmol), and this reaction mixture was refluxed for two hours, and left stirring at room temperature overnight. The creamy white precipitate was filtered, washed with ethanol and dried in vacuum oven at 80° C. for 4 hours. Giving 40.27 g (78% yields).

Workup

  1. temperaturethis reaction mixture was refluxed for two hours
  2. waitleft
  3. filtrationThe creamy white precipitate was filtered
  4. washwashed with ethanol
  5. customdried in vacuum oven at 80° C. for 4 hours
  6. customGiving
  7. custom40.27 g (78% yields)

Sources & evidence

ORD record
ord-d9ab1096a89643b696a7d19deb3f364f
Source dataset
uspto-grants-2014_11
Patent number
US08883325B2

Reaction notes

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